Certificate of Analysis

 

Product Name: SB-505124 hydrochloride 
Catalog Number: M29975
CAS Number: 356559-13-2

Physical and Chemical Properties
Formula: C20H22ClN3O2
Molecular Weight: 371.86
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
Chemical Structure: SB-505124 hydrochloride  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: SB-505124 hydrochloride is a selective inhibitor of TGF-β Receptor type I receptor (ALK4, ALK5, ALK7), with IC50s of 129 nM and 47 nM for ALK4, ALK5, respectively, but it does not inhibit ALK1, 2, 3, or 6.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.