Certificate of Analysis
| Product Name: | SAG |
| Catalog Number: | M14928 |
| CAS Number: | 912545-86-9 |
Physical and Chemical Properties
| Molecular Weight: | 490.06 |
| Solubility: | DMSO ≥ 38 mg/mL |
| Storage: | 2-8°C, protect from light |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | SAG is a potent Smoothened (Smo) receptor agonist (EC50=3 nM; Kd=59 nM). SAG activates the Hedgehog signaling pathway and counteracts Cyclopamine inhibition of Smo. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |