Certificate of Analysis
| Product Name: | Camonsertib (RP-3500) |
| Catalog Number: | M11017 |
| CAS Number: | 2417489-10-0 |
Physical and Chemical Properties
| Formula: | C21H26N6O3 |
| Molecular Weight: | 410.47 |
| Solubility: | DMSO 45 mg/mL |
| Storage: | 4°C, protect from light, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Camonsertib (RP-3500) is an orally potent, selective ATR kinase inhibitor (ATRi) in biochemical assays IC50 1.00 nM. The RP-3500 is 30 times more selective to ATR (IC).50=120 nM), which is 2,000 times > ATM, DNA-PK, and PI3Kα kinase. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |