Certificate of Analysis

 

Product Name: Ro 48-8071
Catalog Number: M3896
CAS Number: 161582-11-2

Physical and Chemical Properties
Formula: C23H27BrFNO2
Molecular Weight: 448.37
Solubility: DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Ro 48-8071 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: Ro 48-8071 is an inhibitor of OSC(Oxidosqualene cyclase; IC50=6.5 nM) that has low-density lipoprotein (LDL) cholesterol lowering activity.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.