Certificate of Analysis

 

Product Name: RMC-0331
Catalog Number: M10882
CAS Number: 2488788-52-7

Physical and Chemical Properties
Formula: C22H25ClF3N5O3
Molecular Weight: 499.91
Solubility: DMSO ≥ 100 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: RMC-0331 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: RMC-0331 (RM-023) is a highly potent, selective, and oral bioavailable SOS1 inhibitor. RMC-0331 is an in vivo tool compound that blocks RAS activation by disrupting RAS-SOS1 interactions.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.