Certificate of Analysis
| Product Name: | RIPK3-IN-1 |
| Catalog Number: | M13405 |
| CAS Number: | 2361139-70-8 |
Physical and Chemical Properties
| Formula: | C29H25FN4O4 |
| Molecular Weight: | 512.53 |
| Solubility: | DMSO : 5 mg/mL |
| Storage: | -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | RIPK3-IN-1 is a RIPK3 TYPE II DFG-out inhibitor with IC50 of 9.1 nM. RIPK3-IN-1 inhibited ABL, BRAF/V599E, MAP4K3 and SRC with IC50 values of 0.37, 0.15, 0.012 and 0.075 μM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |