Certificate of Analysis

 

Product Name: Rigosertib sodium
Catalog Number: M13720
CAS Number: 592542-60-4

Physical and Chemical Properties
Molecular Weight: 473.47
Solubility: DMSO 100 mg/mL; Water ≥ 52 mg/mL
Storage: 2-8°C, sealed
Chemical Structure: Rigosertib sodium Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Rigosertib sodium (ON-01910 sodium) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3K/Akt pathway, promotes the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.