Certificate of Analysis
| Product Name: | Rhosin hydrochloride |
| Catalog Number: | M7194 |
| CAS Number: | 1281870-42-5 |
Physical and Chemical Properties
| Formula: | C20H18N6O.HCl |
| Molecular Weight: | 394.86 |
| Form: | Solid |
| Solubility: | DMSO 50 mg/mL; Water 17 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Rhosin hydrochloride is a rho GTPase inhibitor. Rhosin hydrochloride specifically binds to RhoA to inhibit RhoA-GEF interaction with a Kd of ~ 0.4 uM. Rhosin hydrochloride promotes stress resiliency through enhancing D1-MSN plasticity and reducing hyperexcitability. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |