Certificate of Analysis


Catalog Number: M1669
Product Name: Regorafenib
CAS Number: 755037-03-7

Physical and Chemical Properties
Formula: C21H15ClF4N4O3
Molecular Weight: 482.82
Solubility: DMSO ≥ 100 mg/mL
Storage: at -20°C
Chemical Structure: Regorafenib Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: Regorafenib (BAY 73-4506) is a novel oral multikinase inhibitor of c-KIT, VEGFR2, B-Raf with IC50s of 17, 40 and 69 nM respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.