Certificate of Analysis
| Product Name: | Recombinant Mouse DKK-1 (CHO) |
| Catalog Number: | M21663 |
Physical and Chemical Properties
| Solubility: | Reconstitute the lyophilized powder in ddH₂O or PBS to 100 μg/ml |
| Storage: | Stored at ≤ -20°C, stable for 6 months after receipt |
Analytical Data
| QC Standard: | >95%, Endotoxin < 0.2 EU/μg |
Product Information
| Description: | Dickkopf related protein 1 (DKK-1) is a chemokine that belongs to the DKK protein family, promotes LRP6 internalization and degradation as it forms a ternary complex with the cell surface receptor Kremen. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. ED50 < 6.0 µg/ml, measured in stimulation of alkaline phosphatase activity using CCl-226 cells. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |