Certificate of Analysis

 

Product Name: Rotigotine Hydrochloride
Catalog Number: M3818
CAS Number: 125572-93-2

Physical and Chemical Properties
Formula: C19H23D3ClNOS
Molecular Weight: 351.93
Solubility: DMSO ≥ 40 mg/mL; Water 4 mg/mL (ultrasonic and warming and heat to 60°C)
Storage: 4°C, dry, sealed
Chemical Structure: Rotigotine Hydrochloride Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Rotigotine Hydrochloride (N-0923 Hydrochloride) is a full agonist of dopamine receptor, a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor, with Ki of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors, and dopamine D1 receptor.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.