Certificate of Analysis
| Product Name: | R547 |
| Catalog Number: | M1740 |
| CAS Number: | 741713-40-6 |
Physical and Chemical Properties
| Formula: | C18H21F2N5O4S |
| Molecular Weight: | 441.45 |
| Solubility: | DMSO 70 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 100.00% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | R547 is a potent and selective ATP-competitive CDK inhibitor, with Ki values of 2 nM, 3 nM and 1 nM for CDK1/cyclin B, CDK2/cyclin E and CDK4/cyclin D1, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |