Product Name: | R-406 |
Catalog Number: | M1767 |
CAS Number: | 841290-80-0 |
Formula: | C22H23FN6O5 |
Molecular Weight: | 470.45 |
Solubility: | DMSO 11 mg/mL |
Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Chemical Structure: | ![]() |
HPLC: | Shows Min >99% purity |
H-NMR: | Consistent with structure |
Description: | R406 is an orally bioavailable and selective inhibitor of spleen tyrosine kinase (Syk) with the IC50 of 41nM and Ki value of 30 nM. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |