| Product Name: | Pyrrothiogatain |
| Catalog Number: | M66390 |
| CAS Number: | 477888-48-5 |
| Formula: | C11H11NO2S |
| Molecular Weight: | 221.28 |
| Solubility: | DMSO 90 mg/mL |
| Storage: | -20°C, protect from light |
| Chemical Structure: | ![]() |
| Description: | Pyrrothiogatain is a transcription factor GATA3 inhibitor with an IC50 of 54.7 μM. Pyrrothiogatain inhibits the DNA-binding activity of GATA3 and inhibits the T helper 2 (Th2) cell differentiation and expression of Th2 cytokines. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |