Certificate of Analysis

 

Product Name: Pyrotinib dimaleate
Catalog Number: M14140
CAS Number: 1397922-61-0

Physical and Chemical Properties
Molecular Weight: 815.22
Solubility: Water ≥ 106 mg/mL
Storage: 2-8°C, dry, sealed
Chemical Structure: Pyrotinib dimaleate Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Pyrotinib dimaleate (SHR-1258 dimaleate) is a potent and selective EGFR/HER2 dual inhibitor with IC50s of 13 and 38 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.