Certificate of Analysis
| Product Name: | PY-60 |
| Catalog Number: | M21083 |
| CAS Number: | 2765218-56-0 |
Physical and Chemical Properties
| Formula: | C16H15N3O2S |
| Molecular Weight: | 313.37 |
| Solubility: | DMSO ≥ 65 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | PY-60 is a specific activator (Kd=1.4 µM) of YAP transcriptional activity targeting membrane associated protein A2 (ANXA2).PY-60 binds directly to ANXA2 and antagonizes its normal cellular function of inhibiting YAP activity. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |