Certificate of Analysis
| Product Name: | PXS-5153A monohydrochloride |
| Catalog Number: | M31063 |
Physical and Chemical Properties
| Formula: | C20H24ClFN4O2S |
| Molecular Weight: | 438.95 |
| Form: | Solid |
| Solubility: | DMSO 125 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage: | 4°C, dry, sealed |
Analytical Data
| QC Standard: | ≥99.0% |
Product Information
| Description: | PXS-5153A monohydrochloride is a potent, selective, orally active and fast-acting lysyl oxidase like 2/3 enzymatic (LOXL2/LOXL3) inhibitor, with an IC50 of <40 nM for LOXL2 across all mammalian species and an IC50 of 63 nM for human LOXL3. PXS-5153A monohydrochloride could reduce crosslinks and ameliorates fibrosis. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |