Certificate of Analysis

 

Product Name: PV-1019
Catalog Number: M58411
CAS Number: 1093793-05-5

Physical and Chemical Properties
Formula: C18H17N7O3
Molecular Weight: 379.37
Solubility: DMSO 30 mg/mL (ultrasonic and adjust pH to 3 with 1M HCL)
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: PV-1019 Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: PV-1019 (NSC 744039) is a potent, selective Chk2 inhibitor with an IC50 value of 24 nM. PV-1019 inhibits IR-induced apoptosis.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.