Certificate of Analysis
| Product Name: | PU139 |
| Catalog Number: | M28625 |
| CAS Number: | 158093-65-3 |
Physical and Chemical Properties
| Formula: | C12H7FN2OS |
| Molecular Weight: | 246.26 |
| Form: | Solid |
| Solubility: | DMSO 10 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage: | 4°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | PU139 is a potent pan-histone acetyltransferase (HAT) inhibitor. PU139 blocks the HATs Gcn5, p300/CBP-associated factor (PCAF), CREB (cAMP response element-binding) protein (CBP) and p300 with IC50s of 8.39, 9.74, 2.49 and 5.35 μM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |