Certificate of Analysis
| Product Name: | LC-2 |
| Catalog Number: | M10385 |
| CAS Number: | 2502156-03-6 |
Physical and Chemical Properties
| Formula: | C59H71ClFN11O7S |
| Molecular Weight: | 1132.78 |
| Solubility: | DMSO ≥ 30 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | LC-2 is a potent first-in-class PROTAC capable of degrading endogenous KRAS G12C, with DC50s between 0.25 and 0.76 μM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |