Certificate of Analysis

 

Product Name: PROTAC IRAK4 degrader-1 
Catalog Number: M29530
CAS Number: 2360533-90-8

Physical and Chemical Properties
Formula: C44H39F3N12O7
Molecular Weight: 904.85
Form: Solid
Solubility: DMSO 100 mg/mL (ultrasonic)
Storage: -20°C, dry, sealed
Chemical Structure: PROTAC IRAK4 degrader-1  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: PROTAC IRAK4 degrader-1 is a Cereblon-based PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader, makes <20%, >20-50%, and >50% IRAK4 degradation at 0.01, 0.1, and 1 μM in OCI-LY-10 cells, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.