Certificate of Analysis

 

Product Name: Propargyl-C1-NHS ester
Catalog Number: M49828
CAS Number: 132178-37-1

Physical and Chemical Properties
Formula: C9H9NO4
Molecular Weight: 195.17
Form: Solid
Solubility: DMSO 100 mg/mL
Storage: -20°C, protect from light, dry, sealed
Chemical Structure: Propargyl-C1-NHS ester Structure
Analytical Data
QC Standard: >99.0%
H-NMR: Consistent with structure
Product Information
Description: Propargyl-C1-NHS ester is a non-degradable linker that can be used to synthesize antibody coupled active molecules (ADCs). In addition, Propargyl-C1-NHS ester is a click chemistry reagent. It contains an Alkyne moiety and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an Azide moiety.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.