Certificate of Analysis
| Product Name: | PR-619 |
| Catalog Number: | M2565 |
| CAS Number: | 2645-32-1 |
Physical and Chemical Properties
| Formula: | C7H5N5S2 |
| Molecular Weight: | 223.28 |
| Solubility: | DMSO 21 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.24% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | PR-619 is a broad-spectrum reversible DUB (deubiquitinating enzyme) inhibitor of USP2, USP4, USP5, USP7 and USP8 with an EC50 of 3-9 μM. PR-619 also induces endoplasmic reticulum stress and endoplasmic reticulum stress-associated apoptosis. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |