Certificate of Analysis

 

Product Name: PLX51107
Catalog Number: M9100
CAS Number: 1627929-55-8

Physical and Chemical Properties
Formula: C26H22N4O3
Molecular Weight: 438.48
Solubility: DMSO: ≥ 60 mg/mL (Need warming)
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: PLX51107 Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: PLX51107 is a potent and selective BET inhibitor, with Kds of 1.6, 2.1, 1.7, and 5 nM for BD1 and 5.9, 6.2, 6.1, and 120 nM for BD2 of BRD2, BRD3, BRD4, and BRDT, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.