Certificate of Analysis


Catalog Number: M1761
Product Name: PLX4032
CAS Number: 918504-65-1

Physical and Chemical Properties
Formula: C23H18ClF2N3O3S
Molecular Weight: 489.92
Solubility: DMSO 60 mg/mL
Storage: at -20°C
Chemical Structure: PLX4032 Structure
Analytical Data
HPLC: Shows Min 99.34% purity
H-NMR: Consistent with structure
Product Information
Description: PLX4032 (Vemurafenib, RG7204, RO5185426 and Zelboraf) is a highly selective B-Raf enzyme inhibitor with an IC50 of 44 nM against V600E-mutant BRAF.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.