Certificate of Analysis
| Product Name: | PLN-1474 |
| Catalog Number: | M45153 |
| CAS Number: | 2408065-32-5 |
Physical and Chemical Properties
| Formula: | C24H37N3O4 |
| Molecular Weight: | 431.57 |
| Form: | Solid |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | PLN-1474 is an orally active, selective ανβ1 integrin inhibitor with an IC50 value of <50 nM.PLN-1474 significantly reduces hepatic pSMAD3/SMAD3 levels, hepatic collagen gene expression, and hepatic OHP concentration in a mouse model of liver fibrosis. It can be used in studies related to liver cirrhosis and fibrosis. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |