Certificate of Analysis
| Product Name: | PK14105 |
| Catalog Number: | M27751 |
| CAS Number: | 107257-28-3 |
Physical and Chemical Properties
| Formula: | C21H20FN3O3 |
| Molecular Weight: | 381.4 |
| Form: | Solid |
| Solubility: | DMSO ≥ 30 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | PK14105 is a biological evaluation as a potential radioligand for PET studies of PBBS receptors. in vivo binding experiments, in which PK 14105 was injected into rats with unilaterally lesioned striata, demonstrate that PK 14105 rapidly crosses the blood-brain-barrier and that there is a marked retention of radioactivity in the lesioned striatum not seen in the unlesioned striatum or cerebellar vermis. It can also inhibit receptor ligands, calcium channel ligands and co-transporter in all salivary glands. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |