Product Name: | PIK-III |
Catalog Number: | M8998 |
CAS Number: | 1383716-40-2 |
Formula: | C17H17N7 |
Molecular Weight: | 319.36 |
Solubility: | DMSO: ≥ 30 mg/mL |
Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Chemical Structure: | ![]() |
QC Standard: | >99.0% |
H-NMR: | Consistent with structure |
Description: | PIK-III (also known as VPS34-IN2) is a potent and selective inhibitor of VPS34 enzymatic activity, with IC50s of 18 nM and 1.2 μM for VPS34 and PI(3)Kδ, respectively. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |