Certificate of Analysis

 

Product Name: Pifithrin-α, p-Nitro, Cyclic
Catalog Number: M58435
CAS Number: 60477-38-5

Physical and Chemical Properties
Formula: C15H13N3O2S
Molecular Weight: 299.35
Form: Solid
Solubility: DMF 9 mg/mL; DMSO 3 mg/mL
Storage: -20°C, sealed
Chemical Structure: Pifithrin-α, p-Nitro, Cyclic Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: Pifithrin-α, p-Nitro, Cyclic (PFN-α) is cell-permeable and active-form p53 inhibitor. Pifithrin-α, p-Nitro, Cyclic behaves as a p53 posttranscriptional activity inhibitor. Pifithrin-α, p-Nitro, Cyclic do not prevent p53 phosphorylation on the S15 residue.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.