Certificate of Analysis
| Product Name: | PFK-015 |
| Catalog Number: | M4913 |
| CAS Number: | 4382-63-2 |
Physical and Chemical Properties
| Formula: | C17H12N2O |
| Molecular Weight: | 260.29 |
| Solubility: | DMSO 19 mg/mL warmed |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.27% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | PFK-015 is a potent and selective 6-phosphofructo-2-kinase (PFKFB3) inhibitor. PFK-015 inhibits recombinant PFKFB3 with an IC50 value of 110 nM and inhibits PFKFB3 activity in cancer cells with an IC50 value of 20 nM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |