Certificate of Analysis
| Product Name: | PFK-158 |
| Catalog Number: | M6727 |
| CAS Number: | 1462249-75-7 |
Physical and Chemical Properties
| Formula: | C18H11F3N2O |
| Molecular Weight: | 328.29 |
| Solubility: | DMSO: ≥ 25 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 98.17% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | PFK-158, also known as ACT-PFK-158, is a potent and selective inhibitor of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFK-2/FBPase) isoform 3 (PFKFB3) with potential antineoplastic activity. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |