Certificate of Analysis

 

Product Name: Mardepodect hydrochloride
Catalog Number: M29161
CAS Number: 2070014-78-5

Physical and Chemical Properties
Formula: C25H21ClN4O
Molecular Weight: 428.91
Form: Solid
Solubility: DMSO 25 mg/mL (ultrasonic)
Storage: 4°C, dry, sealed
Chemical Structure: Mardepodect hydrochloride Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: Mardepodect hydrochloride (PF-2545920 hydrochloride) is a potent, orally active and selective PDE10A inhibitor with an IC50 of 0.37 nM, with >1000-fold selectivity over other PDEs. Mardepodect hydrochloride can cross the blood-brain barrier.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.