Certificate of Analysis
| Product Name: | PF-07321332 (Nirmatrelvir) |
| Catalog Number: | M10594 |
| CAS Number: | 2628280-40-8 |
Physical and Chemical Properties
| Formula: | C23H32F3N5O4 |
| Molecular Weight: | 499.53 |
| Solubility: | DMSO >100 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.37% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | PF-07321332 (Nirmatrelvir) is an orally bioavailable 3C-like protease (3CLPRO) inhibitor with an ki of 3.11 nM. PF-07321332 binds directly to the catalytic cysteine (Cys145) residue of the enzyme. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |