Certificate of Analysis
| Product Name: | PF-07220060 |
| Catalog Number: | M45136 |
| CAS Number: | 2380321-51-5 |
Physical and Chemical Properties
| Formula: | C22H27ClFN5O3 |
| Molecular Weight: | 463.93 |
| Form: | Solid |
| Solubility: | DMSO >100 mg/mL |
| Storage: | 4°C, protect from light |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | PF-07220060 is a potent CDK4/CDK6 inhibitor with Ki values of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |