Certificate of Analysis

 

Product Name: Brepocitinib P-Tosylate
Catalog Number: M9853
CAS Number: 2140301-96-6

Physical and Chemical Properties
Formula: C25H29F2N7O4S
Molecular Weight: 561.60
Solubility: DMSO 57 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Brepocitinib P-Tosylate Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: PF-06700841 (Brepocitinib) tosylate is a dual inhibitor of JAK1 and TYK2, with IC50 values of 17 nM and 23 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.