Certificate of Analysis

 

Product Name: PF-06446846 
Catalog Number: M28735
CAS Number: 1632250-49-7

Physical and Chemical Properties
Formula: C22H20ClN7O
Molecular Weight: 433.89
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
Chemical Structure: PF-06446846  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: PF-06446846 is an orally active proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor. PF-06446846 directly and selectively inhibits translation of PCSK9 by stalling the 80S ribosome in the proximity of codon region.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.