Certificate of Analysis
| Product Name: | PF-05105679 |
| Catalog Number: | M28327 |
| CAS Number: | 1398583-31-7 |
Physical and Chemical Properties
| Formula: | C26H21FN2O3 |
| Molecular Weight: | 428.45 |
| Form: | Solid |
| Solubility: | DMSO 125 mg/mL (ultrasonic) |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | PF-05105679 is an orally active and selective TRPM8 antagonist with an IC50 of 103 nM. PF-05105679 has the potential for cold-related pain. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |