Certificate of Analysis

 

Product Name: PF-03654746 Tosylate 
Catalog Number: M27689
CAS Number: 1039399-17-1

Physical and Chemical Properties
Formula: C25H32F2N2O4S
Molecular Weight: 494.59
Form: Solid
Solubility: Water ≥ 8.4 mg/mL
Storage: 4°C, dry, sealed
Chemical Structure: PF-03654746 Tosylate  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: PF-03654746 Tosylate is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 Tosylate reduces allergen-induced nasal symptoms. PF-03654746 Tosylate has potential for treatment of human cognitive disorders, improves cognitive efficacy and disease-modifying effects in Alzheimer's disease (AD).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.