Certificate of Analysis

 

Product Name: PEG2000-C-DMG
Catalog Number: M49799
CAS Number: 1019000-64-6

Physical and Chemical Properties
Formula: C126H249NO52
Molecular Weight: 2610.29
Form: Solid
Solubility: DMSO 100 mg/mL
Storage: -20°C
Chemical Structure: PEG2000-C-DMG Structure
Analytical Data
QC Standard: >99.0%
H-NMR: Consistent with structure
Product Information
Description: PEG2000-C-DMG is a PEGylated modified lipid that can be used to prepare Onpattro, a liver-directed investigational RNAi potent reagent that reduces the production of mutant and wild-type thyroxine carrier protein by targeting the 3′ untranslated region of the thyroxine carrier protein mRNA, a process that is utilized to reduce the production of mutant and wild-type thyroxine carrier proteins.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.