Certificate of Analysis
| Product Name: | PDK1-IN-RS2 |
| Catalog Number: | M28769 |
| CAS Number: | 1643958-89-7 |
Physical and Chemical Properties
| Formula: | C15H9ClN2O2S3 |
| Molecular Weight: | 380.89 |
| Form: | Solid |
| Solubility: | DMSO 125 mg/mL (ultrasonic) |
| Storage: | Powder -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | PDK1-IN-RS2 is a mimic of peptide docking motif (PIFtide) and is a substrate-selective PDK1 inhibitor with a Kd of 9 μM. PDK1-IN-RS2 suppresses the activation of the downstream kinases S6K1 by PDK1. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |