Certificate of Analysis

 

Product Name: PD166326
Catalog Number: M8118
CAS Number: 185039-91-2

Physical and Chemical Properties
Formula: C21H16Cl2N4O2
Molecular Weight: 427.28
Solubility: DMSO: 2 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: PD166326 Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: PD166326 is an ATP-competitive inhibitor of BCR-ABL and Src kinases, inhibiting Src and Abl with IC50 values of 6 nM and 8 nM, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.