Certificate of Analysis
| Product Name: | PD 0332991 HCL |
| Catalog Number: | M1806 |
| CAS Number: | 827022-32-2 |
Physical and Chemical Properties
| Formula: | C24H29N7O2.HCl |
| Molecular Weight: | 483.99 |
| Solubility: | DMSO 4 mg/mL warmed; Water 30 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.90% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | PD-0332991 HCl is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays, respectively. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |