Certificate of Analysis
| Product Name: | P053 |
| Catalog Number: | M58542 |
| CAS Number: | 2748196-63-4 |
Physical and Chemical Properties
| Formula: | C18H21Cl2NO2 |
| Molecular Weight: | 354.27 |
| Form: | Solid |
| Solubility: | DMSO 60 mg/mL; DMF 30 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥97.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | P053 is a potent, non-competitive and selective ceramide synthase 1 (CerS1) inhibitor wirh an IC50 of 0.5 μM. P053 also acts as an endogenous inhibitor of mitochondrial fatty acid oxidation in muscle. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |