Certificate of Analysis
| Product Name: | OTS186935 hydrochloride |
| Catalog Number: | M31019 |
Physical and Chemical Properties
| Formula: | C25H26ClN5O2.8/5HCl |
| Molecular Weight: | 522.31 |
| Form: | Solid |
| Solubility: | Water 50 mg/mL (ultrasonic); DMSO 25 mg/mL (ultrasonic) |
| Storage: | 4°C, dry, sealed |
Analytical Data
| QC Standard: | ≥99.0% |
Product Information
| Description: | OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. OTS186935 hydrochloride shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 hydrochloride regulates the production of γ-H2AX in cancer cells. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |