Certificate of Analysis

 

Product Name: Tirabrutinib (ONO-4059)
Catalog Number: M5333
CAS Number: 1351636-18-4

Physical and Chemical Properties
Formula: C25H22N6O3
Molecular Weight: 454.48
Solubility: 10mM in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Tirabrutinib (ONO-4059) Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: Tirabrutinib (ONO-4059) is a highly selective, orally bioavailable BTK inhibitor with a potency (IC50) of 2.2 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.