Certificate of Analysis

 

Product Name: NX-2127
Catalog Number: M43813
CAS Number: 2416131-46-7

Physical and Chemical Properties
Formula: C39H45N9O5
Molecular Weight: 719.83
Form: Solid
Storage: 4°C, protect from light
Chemical Structure: NX-2127 Structure
Analytical Data
QC Standard: >99.0%
H-NMR: Consistent with structure
Product Information
Description: NX-2127 is an orally active, potent BTK inhibitor that induces degradation of mutant BTKC481S in cells, as well as inhibits the proliferation of BTKC481S mutant TMD8 cells. In addition, NX-2127 stimulates T cell activation and increases IL-2 production in primary human T cells.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.