Certificate of Analysis
| Product Name: | NVL-655 TFA |
| Catalog Number: | M55234 |
| CAS Number: | 2739866-40-9 (free base) |
Physical and Chemical Properties
| Formula: | C25H23ClF4N6O3 |
| Molecular Weight: | 566.94 |
| Solubility: | DMSO 90 mg/mL |
| Storage: | -20°C, protect from light, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | NVL-655 (ALK-IN-27) TFA is a novel, brain-permeable, selective ALK inhibitor with antitumor activity. For Ba/F3 CLIP1-LTK cells, NVL-655 (ALK-IN-27) TFA has an IC50 of 2.7 nM. It can be used in studies related to ALK-positive non-small cell lung cancer (NSCLC). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |