Certificate of Analysis
| Product Name: | NT219 |
| Catalog Number: | M27918 |
| CAS Number: | 1198078-60-2 |
Physical and Chemical Properties
| Formula: | C16H14BrNO5S |
| Molecular Weight: | 412.26 |
| Form: | Solid |
| Solubility: | DMSO ≥ 100 mg/mL |
| Storage: | -20°C, protect from light, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | NT219 is a potent and dual inhibitor of insulin receptor substrates 1/2 (IRS1/2) and STAT3. IRS1/2 and STAT3 are major signaling junctions regulated by various oncogenes. NT219 affects IRS1/2 degradation and inhibits STAT3 phosphorylation. NT219 has the potential for the research of cancer diseases. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |