Certificate of Analysis
| Product Name: | NS-398 |
| Catalog Number: | M7051 |
| CAS Number: | 123653-11-2 |
Physical and Chemical Properties
| Formula: | C13H18N2O5S |
| Molecular Weight: | 314.36 |
| Solubility: | DMSO 31 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.43% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | NS-398 is a cyclooxygenase-2 (COX-2) inhibitor, selectively inhibits prostaglandin G/H synthase 2/cyclooxygenase 2 (COX-2) activity, with an IC50 of 3.8 μM, and has no effect on COX-1 at 100 μM. NS-398 is a non-steroidal an-inflammatory agent with analgesic and antipyretic effects. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |