Certificate of Analysis
| Product Name: | NLRP3-IN-13 |
| Catalog Number: | M54570 |
| CAS Number: | 1704638-35-6 |
Physical and Chemical Properties
| Formula: | C19H15N3O3S |
| Molecular Weight: | 365.41 |
| Form: | Solid |
| Solubility: | DMSO 50 mg/mL |
| Storage: | 4°C, protect from light, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | NLRP3-IN-13 is a potent and selective NLRP3 inhibitor that inhibits NLRP3 and NLRC4 inflammasomes and inhibits NLRP3-mediated IL-1β production with an IC50 value of 2.1 μM. In addition, NLRP3-IN-13 inhibits NLRP3 ATPase activity.NLRP3-IN-13 may be used in the study of neuroinflammation and inflammatory diseases. NLRP3-IN-13 can be used in the study of neuroinflammatory diseases. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |